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Polynucleotides
Polynucleotides are an exciting, cutting-edge treatment that works wonders for skin rejuvenation. Using ultra-purified DNA fragments derived from salmon, this injectable treatment stimulates your skin’s natural ability to repair, restore, and regenerate itself—leaving you with visible, long-lasting results.
How Polynucleotides Work
Think of polynucleotides as a “fertilizer” for your skin cells. They boost fibroblasts (the building blocks of your skin) to encourage tissue repair and collagen production. Unlike traditional skin boosters or fillers, polynucleotides don’t rely on hyaluronic acid. Instead, they work at a deeper level to enhance skin texture, reduce fine lines and wrinkles, and improve overall skin health.
At Skin Enhance and Wellness in Billericay, I’ve carefully chosen the highest-quality polynucleotide products on the market: Plinest (previously Plenhyage) and Newest.
plinest
Plinest contains the highest concentration of polynucleotides in the market. Research has shown that the benefits of treatment are dependent on the amount of polynucleotides used. Therefore, using the highest concentration delivers the best results. Each syringe contains 40mg of polynucleotides. Plinest has 2 main uses. Firstly, it can be used as a preventative for young skin. Secondly, it can be used as a regenerative in a more mature skin. It has been shown to be particularly beneficial in improving scar tissue. As it stimulates the activity of the skin’s own cells, it is a very natural way of rejuvenation without any risk of overfilling.
Specific benefits of Plinest:
Improves skin quality
Restores skin radiance and freshness
Promotes bio-regeneration
Reduces wrinkles and skin laxity
It is suitable for the face and body, both as a treatment on its own or in combination with other modalities. There are specific formulations available for rejuvenation of the eye area-Plinest Eye or hair (scalp, eyebrows)- Plinest hair.
Newest (polynucleotides + hyaluronic acid)
Specifically designed for mature skin, this innovative product has the synergistic benefits of polynucleotides with the hydrating capacity of hyaluronic acid. Newest also contains mannitol, an additional ingredient that retains moisture and prolongs the effect of hyaluronic acid. This gives multiple benefits to the skin. Firstly, non-crosslinked hyaluronic acid hydrates the skin. Secondly, the polynucleotides stimulate collagen and elastin resulting in a more turgid and supple appearance. Thirdly, the repair initiated by polynucleotides remodels depressed scars. Additionally, the antioxidant activity protects the skin from further damage. Overall, Newest helps rejuvenate mature and dehydrated skin in many ways.
Studies have shown that after treatment, the following were observed:
Significant improvement in overall skin quality and texture
Improvement in wrinkles and skin roughness
Increased elasticity
Reduction in pigmentation
It is suitable for young skin, mature skin, damaged skin, acne scars, and stretch marks. Newest can be used on the face and body.
Plinest Eye
Specifically designed for the delicate skin around the eye area. It has just the right concentration of polynucleotides to give reliable results without excessive swelling. Can be used under the eyes, above the eyes and around the outer corners of the eyes to address crow’s feet to reduce wrinkles and skin laxity providing visible skin tightening effects.
Plinest Hair
Specifically designed for the hair and eyebrow area.
before and after
At a Glance Polynucleotides
NUMBER OF TREATMENTS | Recommended Protocol is 3-4 treatments 3 weeks apart with maintenance programme afterwards. |
PROCEDURE TIME | 20 - 30mins |
RECOVERY TIME | 12 - 48hours |
ANAESTHETIC | Local anesthetic cream |
BACK TO NORMAL | Usually immediate however some may experience swelling which can last a few days. |
FINAL RESULTS | Noticeable improvement 4 weeks after 1 treatment but best results can take up to 3 months. |
DURATION OF RESULTS | Up to 6 months hence maintenance is recommended. |
POSSIBLE COMPLICATIONS | Soreness, redness, skin irritation, bruises, swelling, local inflammation and infection. Allergic reaction has not been seen. |
PRECAUTIONS POST PROCEDURE | 24hrs post treatment: Avoid strenuous exercise/ makeup/sauna/extreme temperatures. 3 days post treatment: Avoid active/prescriptive skincare containing alpha hydroxy acids, beta hydroxy acids. Always use sun protection. |
Contraindications | Pregnancy and Breastfeeding. |
What conditions is this suitable for? | Poor skin laxity, fine lines and wrinkles, scars, stretch marks, pigmentation, rosacea, hair loss. |
Any pre-treatment necessary? | Anyone suffering with cold sores would be advised to have prophylactic treatment. |
Frequently Asked Questions about polynucleotides
Where does the DNA come from?
What if I am allergic to fish?
How do polynucleotides work?
How do polynucleotides work?
What happens during a treatment session?
What can I expect after the treatment?
When will I see results?
How many treatments will I need?
How do I maintain glowing healthy skin?
price guide
Polynucleotides (Plinest or Newest) by Dr Tash
Premium Injectable bio-regenerative treatmentFace or body treatment per syringe £259
A course of 3 sessions (Plinest or Newest) £699
Under-eye rejuvenation Plinest Eye (course of 4 sessions) £799
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